At OHSU four Varian linear accelerators (one Tomo HD, two Trilogy and one NovalisTX with high definition MLC), one ElektaSynergy and one Varian 2100 are used to provide external beam electron and photon radiotherapy.  Image guidance consists of on-board imagers at all LINACs with both kV-kV and cone beam CT capabilities. Calypso radio frequency beacon localization,BrainLab ExacTrac fluoroscopy and VisionRT optical guidance imaging is utilized as part of a full service image guidance program. An in-room diagnostic quality CT scanner is located and mates with NovalisTX table. The department has a Philips Brilliance BigBore CT scanner with respiratory gating capabilities for 4D CT based simulation.

The department also has available a 4D PET CT scanner that can be utilized for biologic functional treatment planning. External beam treatment systems consist of Philips Pinnacle 3, Varian Eclipse, Nomos CorvusBrainLab iPlan and Monaco system. These systems are used for CT-based 3D treatment planning, inverse modulated radiation therapy (IMRT), dynamic conformal arc therapy, stereotactic body radiotherapy, RapidArcVMAT and Linac-based radiosurgery. The department uses high-dose rate (HDR) Iridium-192 for the majority of its brachytherapy needs. In addition, brachytherapy sources, and a strontium applicator are kept in the department.  Radioactive Iodine-125 seeds and Iridium-192 are ordered for individual cases as needed.  We have an active I-125 eye plaque brachytherapy program for choroidal melanomas with the Casey Eye Institute using the BeBig treatment planning system.  We have an interstitial brachytherapy program which includes therapy for prostate cancer, soft tissue sarcoma and even for lung cancers participating in an ACOSOG multi-institutional protocol. We use the Varian Variseed treatment planning system. Intra-operative breast treatments are also offered with the Zeiss Intrabeam device.